A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Katti, Trupti V
- A Study of Endometrial Etiological Spectrum in Causation of Infertility in Gulberga, Karnataka
Authors
1 Dept of Pathology, Navodaya Medical College (NMC), Raichur, Karnataka, IN
2 Dept. of Pathology, M.R.Medical College (MRMC), Gulbarga, Karnataka, IN
Source
Indian Journal of Public Health Research & Development, Vol 4, No 4 (2013), Pagination: 38-44Abstract
Background: Infertility is world wide problem and is defined as inability of couple to achieve conception after one year of unprotected coitus. The purpose of investigation in infertile couple is to assess chance of achieving pregnancy and to identify treatable factors.
Aims:
1)To determine causes of primary and secondary infertility by endometrium patterns.
2)To assess importance of luteal phase deficiency in infertility.
3)To determine endometrial glycogen content and its possible correlation with infertility.
4)To determine incidence of tubercular endometritis as an etiological factor.
Settings and design: It is 5 year prospective study . Females complaining of primary or secondary infertility were included.
Materials and Method: During our 5 years study (July 2004 to June 2009), we received 230 endometrial currettings (178 cases-primary infertility and 52-secondary infertility) in Pathology Department, at M.R.Medical College, Gulbarga. Routine histopathological processing and staining was done with hematoxylin & eosin. Periodic acid Schiff stain was done for 50 cases of infertility and 25 cases of proved fertility (control).
Results and Conclusion: Histopathologically, endometrium showed secretory phase- 149, proliferative (anovulatory cycles)-53, tubercular endometritis-7 and endometrial hyperplasia-15.Luteal phase defect (LPD) was observed in 39 cases with glycogen deficiency (43.8%).Thus, anovulatory endometrium, LPD and endometrial hyperplasia formed major etiology, whereas endometriosis and tuberculosis formed minor group. Glycogen deficiency was seen mainly in LPD. Thus, endometrial biopsy is an important investigation in developing countries where expensive, immunological and hormonal assays are not easily available or affordable.
Keywords
Endometrium, Infertility, Anovulatory, Luteal Phase Defect, TuberculosisReferences
- Dawn C.S text books of Gynecology,Contraception & Demography 14th edition 2003,11;103-114.
- Howkins & Bourne Shaw’s text books of Gynecology 12th edition 1999, 13;152-168.
- Leon speroff, Marc AF .Clinical gynecologic endocrinology and infertility:6th edition, :Lippincot Williams and Wilkins 1999.26;1013- 1037.
- Drissen P.J Holwedra .Putte J Kremmer:The significance of dating on endometrial biopsy for the prognosis of the infertile couple. Int .J. Fertile 1980;25:112.
- Jones G.S the luteal phase defect fertile steril 1976;27:351
- Noyes R. W, Hertig A. T, Rock J. Dating the endometrial biopsy. Fertile Sterile 1950; 1:3.
- Dallenbach- Hellwag, Histopathology of the endometrium. 4 edition Sprigner- Verlag 1980.
- Haines and Taylor. Obstretical and Gynaecological Pathology 1995.
- Arzac J. P. and Blanchet E.J, Clinical Endocrinology. 1948;8:315.
- Krishna Mohan V.E Basanti Nair, Sheela shenoy . A histopathological study endometrium in primary sterility .Indian J obst and Gynaec . 1993;43:581-4.
- Rameshkumar K and Thomas .J a endometrial biopsy in women with primary infertility Indian. J obst and Gynaec 1991;9:20.
- Sahmay S oral C caridogan C sentruch L Stosu T endometrial biopsy findings in infertility analysis of 12,949 cases int J Fertil Menopausal study 1995;40(6) :316
- Amarnath Bhide, Parulkar , Bhattacharya genital tuberculosis in women J obst and gynaec inaia 1987;37:576
- Zawar MP, Deshpande NM, Gadgil PA.Mahanta A.Hsitopathological study of endometrium in infertility . Indian j Pathol Microbial 2003;46 (4):630-633.
- Girish C.J A histopathological study of endometrium in infertility with special reference to its glycogen content dissertation submitted to RGUHS 2006;6:80
- Neil .S. Shastrabudhe, sharmila shinde endometrium in infertility Indian J of obst and Gynaec 2011;51:100.
- Tyagi S.P Nishant IA, Najma Abbassi, Prasad M .Shaista M.Endometrial tuberculosis J of obst and gyn of India 1977;27:935-40.
- Gupta A.N Agarwal S, Vashista K study of endometrium in infertile women. J.Obst and Gynaec India 1980;8:27
- Wentz.A.C, Endometrial biopsy in evaluation of infertility. Fertile steril 1980; 33:2.
- Michel soules, Luteal phase deficiency. The infertile women 1987; 14: 865.
- Vishnu Gopal M Raj Baveja Vatsala somont tubercular endometritis J of obst and gynaec of India 1971;21(1-3):72-77.
- Rajiv Misra S.P Sharma Mrs Jenna Mrs Nalini Pant, D.K Shrivastava female genital tract tuberculosis special reference to sterility in eastern U.P India J obst and Gynaec 1991;9:20.
- Shetty V.G endometrium in infertility .J obst and Gynec India 1959;10:139.
- Sareen P.M, Roopam Karla, S.K. Lodha, V.B Karla, Significance of endometrium glycogen in primary sterility. Indian J.Obst and Gynaec 1984; 34:877.
- Falk V, Ludriksson K, Agnon C. Genital tuberculosis in women. Am J. Obst 1980;138:933.
- Fox H, Buckely C.H, Histopathological study of endometrium in infertility cases.Recent advances in histopathology 1981.
- Hughes EC. Am. J. of Obst and Gync. 1945;49: 10-14.
- Sharma, S C.Banerjee A K: Endometrial glycogen in sterility: J Obst and Gynaec India:1984:34:1073
- Spectrum of Benign Upper Gastro Intestinal Lesions Diagnosed by Endoscopic Examination Followed by Biopsy
Authors
1 Dept of Pathology, Navodaya Medical College (NMC), Raichur, Karnataka, IN
2 Dept. of Pathology, Goa Medical College (GMC), Bambolim, Goa, IN
3 Dept. of Pathology, GMC, Bambolim, Goa, IN
Source
Indian Journal of Public Health Research & Development, Vol 4, No 4 (2013), Pagination: 231-237Abstract
Background: Upper gastrointestinal lesions run the gamut from inflammatory lesions to carcinoma. Endoscopy has greatly facilitated biopsy diagnosis. Present study reveals spectrum of benign upper gastro intestinal lesions obtained by endoscopic biopsy.
Aims:
1) To study types of lesions
2) Comparison with Indian and Western literature.
Setting & Design: It is observational study. Patients with upper gastro-intestinal complaints were subjected to endoscopy and biopsy of lesions observed.
Material and Method: 701 upper gastro-intestinal biopsies were received and 283 were benign in three years study. The tissue was routinely processed and stained with hematoxylin and eosin.
Results and Conclusion: Majority of biopsies were gastric. Interesting lesions were - eosinophilic gastritis without parasitic infestation or eosinophilia; trichuris trichura in stomach; adult pyloric stenosis, fundic gland polyp with parietal cell hyperplasia in omeprazole user, ampullary heterotopic pancreas and duodenal ankylostomiasis. When compared with indian and western literature, this study too proves that endoscopic biopsy is useful in diagnosis, reducing surgeries.
Keywords
Benign Upper Gastro Intestinal Lesions, Endoscopic Biopsy, Interesting PathologiesReferences
- William S. Haubrich , James M. Edmonson : Chapter 1 History of Endoscopy: Principles and concepts of gastroenterologic endoscopy: 2-15
- Hopkins H H: Optical principles of endoscope. In Berci G Ed Endoscopy Ed.2 New York Appleton-Centary-Croft 1976:3-26
- Practical Gastrointestinal Endoscopy: The Fundamentals: Peter B Cotton and Christopher B Williams 5th edition: Chapter 2 Equipment : 6-25
- Colour Atlas of differential diagnosis in Exfoliative and Aspiration cytopathology: By Sudha R Kini; Chapter Eight Alimentary Tract- Esophagus/Gastrointestinal Tract and Biliary Tract:171-177
- Ricardo H. Bardales, Michael W. Stanley, Donald D. Simpson, Sandra J. Baker, Cindy T. Steele, Robert F. Schaefer and Celeste N. Powers: Diagnostic value of brush cytology in the diagnosis of duodenal, biliary and ampullary neoplasms: American Journal of Clinical Pathology May 1998:109;5:540-548
- Anderson’s Pathology (Tenth edition)-Ivan Damjanor and James Linder Vol.2:Chapter 53- Stomach and Duodenum:1661-1707
- Anderson’s Pathology (Tenth edition)-Ivan Damjanor and James Linder Vol.2:Chapter 52- Esophagus:1647-1660
- Kaiyo Takubo, Koji Sasajima, Kiyohiko Yamashita, Yoichi Tanaka, and Kichishiro Fujita: Double Muscularis Mucosae in Barrett’s esophagus : Human pathology 1991;22;1158-1161
- David B. Skinner, Bruno C. Walther, Robert H. Riddell, Helmut Schmidt, Clement Iascone , Thomas R Demeester: Barrett’s Esophagus- Comparison of Benign and Malignant Cases: Annual Surgery Oct 1983;198;4:554-564
- Punia RS, Arya S, Mohan H, Duseja A, Bal A; Spectrum of clinico-pathological changes in Barrett oesophagus: J Assoc Physicians India. 2006 Mar;54:187-189.
- W. Rumfield, D. Jenkins, and B.B Scott: Unexpected gastro - esophageal candidiasis - an endoscopic survey : The British society of Gastroenterology : Gut 1980;21;A895
- Sternberg’s Diagnostic Surgical Pathology (Fourth edition) Stacey. E. Mills, Darryl Carter, Joel K. Greenson, Harold. A. Oberman, Victor Reuter, Mar. H. Stoler Vol.2:Chapter 31- Esophagus:1399-1434
- Nikhil Moorchung, A N Srivastava, N K Gupta, BR Achyut, Balraj Mittal: The histopathology of chronic gastritis: Indian Journal of Pathology and Microbiology 2007;50;1:18-24
- Saeed Afzal, Mumtaz Ahmad, Azhar Mubarik, Farrukh Saeed, Shahid Rafi, Nasir Saleem, Ayaz Hussain Qur ;MORPHOLOGICAL SPECTRUM OF GASTRIC LESIONS - ENDOSCOPIC BIOPSY FINDINGS ;Pakistan Armed forces medical journal June 2006: 2
- Piyalee Gupta, L B Pandey, R N Behra, M K Rai, R. Chandera: Role of ELISA in H. pylori detection and its correlation with urease test: Indian Journal of Pathology and Microbiology 2003;46;3:511-514
- Vijaya V. Mysorekar, Chitralekha P Dandekar, BS Satya Prakash, Abhijit Sarkar: Role of imprint cytology in the diagnosis of gastrointestinal tract malignancies: Indian Journal of Pathology and Microbiology 2003;46;1:37-43
- Sternberg’s Diagnostic Surgical Pathology (Fourth edition) Stacey. E. Mills, Darryl Carter, Joel K. Greenson, Harold. A. Oberman, Victor Reuter, Mar. H. Stoler Vol.2:Chapter 32 Stomach -:1435-1474
- Thida Lwin, Shelby D Melton , Robert M Genta: Eosinophilic gastritis: histopathological characterization and quantification of the normal gastric eosinophil content: Modern Pathology 17 December 2010
- Farhad Navab, Martin S. Kleinman, Kenneth Algazy., Eric Schenk., Michael D. Turner: Endoscopic diagnosis of eosinophilic gastritis : Gastrointestinal Endoscopy Nov 1972;19;2: 67-69.
- Hong S T, Lim H S, Kim D H, Kim S J : A case of gastroenteritis associated with gastric trichuriasis: J Korean Med Sci. Jun 2003;18;3:429-432.
- Alireza Zarineh, Marino E. Leon, Reda S. Saad, and Jan F. Silverman: Idiopathic Hypertrophic Pyloric Stenosis in an Adult, a Potential Mimic of Gastric Carcinoma- Case Report: Pathology Research International : 2010: Article ID 614280, 4 pages
- Susan C. Abrahim, Vikesh K. Singh, John H. Yardley and Tsung The Wu: Hyperplastic polyps of the stomach-Associations with histologic patterns of gastritis and gastric atrophy: American Journal of Surgical Pathology 2001;25;4;500-507.
- Enrico-G. Cristallini, Stefano Ascani, Giovanni B. Bolis: Association between histologic type of polyp and carcinoma in the stomach: Gastrointestinal Endoscopy 1992; 38; 481-484.
- Takuji Nakamura, Gen-Ichi Nakano: Histopathological classification and malignant change in gastric polyp: Journal of Clinical Pathology Feb 1985: 754-764.
- David J. Bjorkman et al : Proton-Pump Inhibitors and Fundic-Gland Polyps : Journal Watch Gastroenterology February 23, 2007.
- Paolo Declich, Maria Sironi : Fundic gland polyps-An innocuous curiosity possibly with important pathological associations: Human Pathology Nov 1997;28;11:1328
- Patrick L. Fitzgobbons, Cornelius P. Dooley, Hartley Cohen and Maria D. Appleman: Prevalence of gastric metaplasia, inflammation and Campylobacter pylori in the duodenum of members of a normal population: American Journal of Clinical Pathology 1988;90;6:711-714.
- Mohamed, A. E.; Ghandour, Z. M.; Al-Karawi, M. A.; Yasawy, M. I.; Sammak, B.:Gastrointestinal parasites presentations and histological diagnosis from endoscopic biopsies and surgical specimens; Saudi Medical Journal 2000;21; 7; 629-634.
- Sang Soo Shin, Yong Yeon Jeong and Heoung Keun Kang ; Giant Heterotopic Pancreas in the Jejunal Mesentery- Case Report : AJR 2007; 189:W262-W26.
- Zhou Yuan, Jie Chen, Qi Zheng, Xin-Yu Huang, Zhe Yang, Juan Tang: Heterotopic pancreas in the gastrointestinal tract -CASE REPORT: WORld J of Gastroenterology 2009; Aug 7;15;29: 3701-3703.
- Atindriya Biswas, Ehab A Husain, Roger M Feakins, Ajit T Abraham: Heterotopic Pancreas Mimicking Cholangiocarcinoma- Case Report and Literature Review: JOP. J Pancreas (Online) 2007; 8(1):28-34.
- Hong Liu, Lisa R. Dixon, and Thomas J. George; Pancreatic Heterotopia Masquerading as Duodenal Carcinoid Gastrointest; Cancer Res. 2009 May–Jun; 3; 3: 118–120.
- Giovanni Cammarota, Paolo Fedeli and Antonio Gasbarrini : Emerging technologies in upper gastrointestinal endoscopy and celiac disease : Gastroenterology & Hepatology 47 ;Jan 2009 :6:1.